Adamax (Non-Amidated)
Non-Amidated Acetylated Semax Analog (Ac-MEHFPGPAG)
Molecular Details
Overview
Adamax is a synthetic peptide supplied for laboratory research use only. The molecular data shown here is taken from the certificate of analysis issued for this batch — molecular formula C₄₄H₆₁N₁₁O₁₃S, with LC-MS identity confirmed at 984 Da. A structurally different compound of roughly 1032 Da is also sold under the Adamax name, so molecular weight is the reliable way to distinguish the two when comparing specifications. Adamax has limited peer-reviewed literature under its own name. The molecular data here is provided for identification; it is not a summary of clinical evidence.
Published Research
Parent Scaffold — Semax / ACTH(4-7) Neuromodulation
In vivo (rodent) · 2006Adamax derives from Semax, an analog of the ACTH(4-10)/(4-7) fragment. Research on the parent Semax scaffold has reported rapid increases in brain-derived neurotrophic factor (BDNF) and modulation of neurotrophic signaling in rodent hippocampus. These findings pertain to the parent compound rather than to the Adamax analog specifically.
Parent Scaffold — Gene Expression in Ischemia Models
Genome-wide profiling (rat) · 2014Studies of the Semax scaffold in ischemic models describe modulation of vascular- and immune-related gene expression. As with all entries here, this reflects research on the parent peptide family; independent published data on the Adamax analog itself is limited.
Analog Design Rationale
Structural / Medicinal chemistry · 2020Adamax applies N-terminal acetylation and a C-terminal Ala-Gly extension to the Semax core — modifications of a type generally intended to influence peptide stability. No peer-reviewed clinical literature specific to the Adamax analog was identified; its profile is presented on the basis of its molecular relationship to Semax.
Key Characteristics
- A Semax analog with a longer peptide chain — the Semax core, N-acetylated and extended at the C-terminus
- Molecular formula C₄₄H₆₁N₁₁O₁₃S, molecular weight 984.11 Da, as stated on the certificate of analysis for this batch (LC-MS identity confirmed at 984 Da)
- No registry entry of its own — no assigned CAS number and no PubChem record, which is unremarkable for an analog that has never been separately registered
- Despite the brand name, the molecular formula on the certificate (C₄₄H₆₁N₁₁O₁₃S) contains no adamantane group
- A structurally different compound of roughly 1032 Da is also sold under the Adamax name — molecular weight is the reliable way to tell the two apart
- A newer designer analog with limited independent peer-reviewed literature; see the Semax profile for parent-scaffold research
Storage & Handling
Store lyophilized powder at –20°C or below. Contains methionine, which is oxidation-prone — minimize exposure to light and air. Reconstituted solutions: refrigerate at 2–8°C and use within 1–2 weeks. Avoid repeated freeze-thaw cycles.
For research purposes only. Not intended for human consumption. This profile summarizes published preclinical literature and does not constitute medical, clinical, or dosage guidance.